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中国人民解放军总医院老年心血管病研究所
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中华老年多器官疾病杂志编辑委员会
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创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
周平,闫超群,胡尚卿,金美林,邵佳凯,石广霞,王丽琼,刘存志.针刺对主观认知下降人群认知功能的调节作用[J].中华老年多器官疾病杂志,2019,18(3):169~173
针刺对主观认知下降人群认知功能的调节作用
Effect of acupuncture on cognitive function of individuals with subjective cognitive decline
投稿时间:2018-12-03  
DOI:10.11915/j.issn.1671-5403.2019.03.033
中文关键词:  针刺;主观认知下降;认知功能;神经心理学量表
英文关键词:acupuncture; subjective cognitive decline; cognitive function; neuropsychological scale
基金项目:国家自然科学基金面上项目(81674055)
作者单位E-mail
周平 首都医科大学附属北京中医医院针灸中心,北京 100010  
闫超群 首都医科大学附属北京中医医院针灸中心,北京 100010  
胡尚卿 北京中医药大学针灸推拿学院,北京100029  
金美林 北京中医药大学针灸推拿学院,北京100029  
邵佳凯 首都医科大学附属北京中医医院针灸中心,北京 100010  
石广霞 首都医科大学附属北京中医医院针灸中心,北京 100010  
王丽琼 北京中医药大学针灸推拿学院,北京100029  
刘存志 北京中医药大学针灸推拿学院,北京100029 lcz623780@126.com 
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中文摘要:
      目的 观察“调和气血,补心益智”针刺法对主观认知下降(SCD)人群认知功能的调节作用。方法 纳入2017年12月至2018年9月期间首都医科大学附属北京中医医院公众号广告平台以及北京地区多个社区义诊招募的SCD者26例,按就诊顺序分为针刺组(n=14)和空白对照组(n=12)。2组受试者在治疗期间均予内科常规治疗,针刺组在常规治疗基础上采用“调和气血,补心益智”针刺法进行为期3个月的针刺治疗,空白对照组进行为期3个月的等待治疗。观察2组受试者治疗前和治疗结束后主观认知下降量表(SCD-Q)、简易智能精神状态量表(MMSE)、动物词语流畅性量表(AFT)、听觉词语学习测验量表(AVLT-H)、形状连线测验A和B量表(TMT A-B)评分以及神经心理学量表综合Z分数的变化情况。采用SPSS 22.0软件进行数据处理。依据数据类型,组间比较分别采用t检验或秩和检验或χ2检验。结果 与治疗前相比,针刺组SCD-Q[(7.35±1.32) vs(3.46±1.63)分]、MMSE[(27.00±1.66) vs(28.32±1.56)分]、AVLT-H即刻回忆[(14.85±2.03) vs(19.14±2.31)分]、AVLT-H短延时回忆[(4.28±1.58) vs(6.64±1.15)分]、AVLT-H长延时回忆[(4.14±1.56) vs(6.57±1.08)分]、AFT[(15.64±4.19) vs(19.36±3.75)分]和综合Z分数[0.03(-0.22,0.24) vs 0.04(-0.30,0.49)分]评分均有显著改善(P<0.05);对照组MMSE评分[(27.16±1.40) vs(26.16±1.52)分]有下降趋势(P<0.05)。与对照组比较,针刺组的SCD-Q[(3.46±1.63) vs(7.20±1.33)分]、MMSE[(28.32±1.56) vs(26.16±1.52)分]、AFT[(19.36±3.75) vs(15.33±5.17)分]、综合Z分数[0.04(-0.30,0.49) vs -0.06(-0.37,0.30)分]评分改善更为明显(P<0.05)。结论 “调和气血,补心益智”针刺法能够明显减少SCD人群对自身认知功能的抱怨,对SCD人群的记忆和言语功能具有较好的调节作用,但对执行功能未见明显影响。
英文摘要:
      Objective To observe the effect of acupuncture maneuver featuring “harmonizing qi and blood and nourishing mind” on cognitive function of people with subjective cognitive decline (SCD). Methods A total of 26 SCD patients were recruited for the studyvia the online bulletin board of Beijing Chinese Medicine Hospital affiliated to Capital Medical University or at gratuitous medical consultation in multiple communities in Beijing from December 2017 to September 2018. They were divided into acupuncture group (n=14) and control group (n=12). For a period of 3 months, both groups received conventional medical therapy, with acupuncture maneuver featuring “harmonizing qi and blood and nourishing mind” being added to the acupuncture group but not to the control group. A comparison was made between the two groups before and after the treatment for subjective cognitive decline questionnaire (SCD-Q), mini-mental state examination (MMSE), animal fluency test (AFT), auditory verbal learning test-Huashan version (AVLT-H), trail-making test A-B (TMT A-B) and Z-composite score. SPSS statistics 22.0 was used for data processing. Depending on the data type, comparison between groups was conducted by Student′s t test or Chi-square test. Results Acupuncture group scored significantly better after the treatment than before the treatment in SCD-Q [(7.35±1.32) vs (3.46±1.63)], MMSE [(27.00±1.66) vs (28.32±1.56)], [JP+1]AVLT-H immediate recall [(14.85±2.03) vs (19.14±2.31)], AVLT-H short delay recall [(4.28±1.58) vs (6.64±1.15)],AVLT-H long delay recall [(4.14±1.56) vs (6.57±1.08)], AFT[(15.64±4.19) vs (19.36±3.75), P < 0.05] and Z-composite score [0.03(-0.22, 0.24) vs 0.04(-0.30, 0.49)] and the control group showed declining MMSE scores [(27.16±1.40) vs(26.16±1.52)](P<0.05). Improvement in the acupuncture group was more significant than the control group in SCD-Q [(3.46±1.63) vs (7.20±1.33) score], MMSE[(28.32±1.56) vs (26.16±1.52) score], AFT[(19.36±3.75) vs (15.33±5.17) score] and Z-composite score [0.04(-0.03, 0.49) vs -0.06(-0.37, 0.30)] (P<0.05). Conclusion Acupuncture maneuver featuring “harmonizing qi and blood and nourishing mind” can significantly reduce the complaints in the SCD patients, exerting positive effects on their memory function and speech function but no obvious effects on their executive function.
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