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中国人民解放军总医院
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中国人民解放军总医院老年心血管病研究所
中国科技出版传媒股份有限公司
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中华老年多器官疾病杂志编辑委员会
100853, 北京市复兴路28号
电话:010-66936756
传真:010-66936756
E-mail: zhlndqg@mode301.cn
创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
曹永生1,唐念中2,戴 煌3,倪竟全3,朱爱华3,慈书平3*.老年退行性心脏瓣膜病与多器官疾病发生的调查分析[J].中华老年多器官疾病杂志,2014,13(10):768~770
老年退行性心脏瓣膜病与多器官疾病发生的调查分析
Senile degenerative heart valvular disease and multiple organ diseases: a clinical study
  
DOI:10.3724/SP.J.1264.2014.000177
中文关键词:  老年人;心脏瓣膜疾病;超声;多器官疾病;临床研究
英文关键词:aged; heart valve diseases; ultrasound; multiple organ diseases; clinical study
基金项目:
作者单位E-mail
曹永生1,唐念中2,戴 煌3,倪竟全3,朱爱华3,慈书平3* 1济南军区总医院干部保健科,济南 250051;2解放军第411医院老干部科,上海 200081;3解放军第359医院老干部科,镇江 212001 cishuping@sohu.com 
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中文摘要:
      目的 分析老年退行性心脏瓣膜病(SDHVD)与多器官疾病的发生状况。方法 老年人3 896例,男2 884例,女1 012例,年龄60~103(78±13)岁。所有研究对象均进行心脏彩超、体检、相关辅助检查,并对多器官疾病进行分析。结果 3 896例患者中,SDHVD1225例(31.4%),无SDHVD2671例(68.6%),SDHVD组与对照组多器官疾病的发病率分别为高血压病 49.3% vs 28.4%,冠心病38.5% vs 23.8%,心力衰竭36.2% vs 17.3%,肺心病6.3% vs 3.1%,脑卒中21.6% vs 9.6%,肾功能不全6.9% vs 3.2%,胃食管反流病21.3% vs 10.3%,两组比较差异均有统计学意义(P<0.05),而糖尿病为11.2% vs 12.1%,两组比较差异无统计学意义(P>0.05)。结论 SDHVD组多器官疾病显著增高,可能由于SDHVD心脏重构改变,血流动力学异常,促发了多器官疾病的发生。
英文摘要:
      Objective To investigate senile degenerative heart valvular diseases (SDHVD) and multiple organ diseases. Methods A multi-center study was carried out in some sanatoriums for retired veteran cadres and their couples from October 2008 to June 2014. There were 3 896 elderly patients recruited (all with full medical records and undergoing overall physical examination every year), including 2 884 males and 1 012 females, with age of (78±13) years (ranging from 60 to 103 years). Clinical data of their echocardiography, physical examination, and auxiliary examination were collected and analyzed for multiple organ diseases. Results Among the 3 896 elderly patients, there were 1 225 having SDHVD (31.4%). The incidences of multiple organ diseases in the SDHVD group and non-SDHVD group were as follows respectively: hypertension 49.3% vs 28.4%, coronary heart disease 38.5% vs 23.8%, heart failure 36.2% vs 17.3%, pulmonary heart disease 6.3% vs 3.1%, stroke 21.6% vs 9.6%, renal insufficiency 6.9% vs 3.2%, gastroesophageal reflux disease 21.3% vs 10.3%, and diabetes mellitus 11.2% vs 12.1%. Significant differences were found in all above incidences except for that of diabetes mellitus between the 2 groups (P<0.05). Conclusion Multiple organ diseases are more common in the elderly suffering from SDHVD. It might be due to that SDHVD induces cardiac remodeling and abnormal hemodynamics, and thus triggers the occurrence and development of multiple organ diseases.
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